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The prevalence of any penile quadrivalent vaccine-preventable HPV genotype was also higher in the pre-vaccination cohort (21 of 177) than in the post-vaccination cohort (11 of 179 0♴8, 0♲4–0♹7), driven by decreases in HPV 6 and 11, but not by 16 and 18. Nevertheless, there was also a significant reduction in anal HPV16 and 18 in the post-vaccination cohort from the pre-vaccination cohort (0♳1, 0♱4–0♶8). The prevalence of any anal quadrivalent vaccine-preventable HPV genotype was higher in the pre-vaccination cohort (54 of 193) than in the post-vaccination cohort (14 of 193 adjusted prevalence ratio 0♲4, 95% CI 0♱4–0♴2), primarily driven by decreases in HPV6, followed by HPV 11, 16, and 18. This study included 400 MSM with a median age of 19 years from sexual health clinics, and the community in Melbourne, with a median number of lifetime male partners, was ten. Published in Lancet Infectious Diseases on May 24, 2021, the HYPER2 study found a significant reduction in vaccine-preventable HPV genotypes in men who have sex with men (MSM) aged 16-20 years following the introduction of the vaccine.Īnd the decrease in anal HPV 16 and 18 may lead to a reduction in the incidence of anal cancer.
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A new study led by Monash University and Alfred Health found a 70% reduction in one type of human papillomavirus (HPV) in gay and bisexual men after the implementation of an HPV vaccination program in 2013.